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Articles tagged with: Sean carroll

Evo devo, video »

[9 Oct 2009 | No Comment]

This video features a talk by Sean Carroll at Strosacker Auditorium in September 2008
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HOX »

[25 Mar 2009 | No Comment]
Top 15 articles on Hox function- Part III

Today in the third and last part of “Top 15 articles on Hox function” series ( In case if you are new here ,the first two parts can be read here and here ),we see five outstanding articles related to Hox function. So here it goes:
11) Study by Passner et al determined the crystal structure of an Ultrabithorax-Extradenticle-DNA complex at 2.4A° resolution, using the minimal polypeptides that form a cooperative heterodimer. It was first of its kind, where crystal structure of proteins was determined on physiological target. The HD …

HOX »

[25 Feb 2009 | No Comment]
Top 15 articles on Hox function- Part I

Ever since the landmark Paper of Ed Lewis in Nature 1978 ,deciphering the Bithorax complex in Fruit fly Drosophila melanogaster ,a number of papers contributed significantly in our understanding hox gene function in Drosophila and other metazoans. Today we take a look at my Favourite 15 Hox articles ( mostly on Drosophila ) that helped understanding function of these master regulators.Remember this list doesn’t include articles related to regulation of Hox genes , but only about discovery and function of Hox genes.
1) No points for guessing correct,The list begins with …

Fundamental, Tools »

[2 Feb 2009 | No Comment]
How Does Antibody staining in Drosophila works?

The most common reason for generating antibodies against a particular protein in Drosophila is to examine its pattern of endogenous expression during development. There are many methods that use the exquisite sensitivity of antibodies to locate a cellular component or a specific molecule (a tissue antigen). This process of localizing proteins in cells of a tissue section exploits the principle of antibodies binding specifically to antigens in biological tissues. The interaction between antibody – antigen can be visualised in different ways like an antibody is conjugated to an enzyme, such …

Evo devo, Tools »

[15 Dec 2008 | No Comment]
How useful are animations in teaching?

Biology classrooms are not the same anymore ,since the advent of Internet teachers are using various formats like multimedia to put their thoughts across to students.The Web allows the incorporation of animation, moving pictures, and sound into lessons, which helps the students understand the subject better and rather in quick time. Everyone will agree with me that students will take more interest in learning when they see experiments in front of their eyes, see microorganisms up close, and use a mouse to navigate images. (156)

Evo devo »

[2 Nov 2008 | No Comment]
An Interview with Sean Carroll

Sean Carroll, a name which needs no introduction in the field of evo devo.Recently PLos genetics published an interview with Sean B Carroll ,where he talks about his journey beginning from the lab of Matt Scott to a scientist and writer of evolution.

Gitschier: Were you the first person in Matt’s lab?
Carroll: Allen Laughon and I were there for day one in Boulder. Allen came from Ray Gesteland’s [lab] in Utah. We took over a lab from a microbiologist, and Boulder hadn’t bothered to clean it. So Al and I …

Evo devo »

[13 Sep 2008 | 3 Comments]
What makes us Humans?

One of the important question in the field of evolution is to understand : What makes us humans? It is well approved now that humans and chimpanzees originate from a common ancestor before diverging from each other some 6 million years ago.Charles Darwin was not provocative in saying that we descended from apes ,indeed we are apes in every form our long arms,habits,temperament and tailless bodies. In order to understand better what differs between humans with their closest living relatives chimps ,scientists have sequenced the genome of Chimpanzees in 2005 …