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[29 Jul 2009 | No Comment]
Freshly crushed garlic better for the heart

A press release related to the benefits of freshly crushed garlic when compared to processed.
A new study reports what scientists term the first scientific evidence that freshly crushed garlic has more potent heart-healthy effects than dried garlic. Scheduled for the Aug. 12 issue of the Journal of Agricultural and Food Chemistry, it also challenges the widespread belief that most of garlic’s benefits are due to its rich array of antioxidants. Instead, garlic’s heart-healthy effects seem to result mainly from hydrogen sulfide, a chemical signaling substance that forms after garlic …

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[29 Jul 2009 | No Comment]

Expansion of transcription factor families correlates with organism complexity. Dr. Marian Walhout and her colleagues have carried out a large-scale systematic analysis of three primary influences on the evolution of functionally divergent transcription factors.

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[29 Jul 2009 | No Comment]
Role of hunchback in Spider Achaearanea tepidariorum

Wim Damen’s lab in University of Cologne is interested in understanding the evolutionary basis of biological pattern formation using spider’s as model system. The chelicerates to which the spiders belong form a monophyletic group that has already split during the Cambrian from the other arthropod groups. Damen’s group famous for studying Spider’s started with Cupiennius salei,a tropical spider and now shifted to another spider species Achaearanea tepidariorum. These spiders can currently be found all over the world. In these spiders males are smaller than the females and range from 3.8 …

Tools »

[23 Jul 2009 | No Comment]
How to identify rosy marker in Drosophila ?

Generation of transgenic Drosophila is possible by microinjection plasmid DNA containing the gene of interest into pole cells (located at one end of embryo) of pre blastoderm embryo. During this particular stage of embryogenesis nuclei are not surrounded by membrane (syncytium stage) and this makes many nuclei accessible for uptake of injected plasmid.
Drosophila transgenesis mainly relies on P-element which was for the first time used by Gerry Rubin and Alan Spradling in 1982.The use of p element for transformation was a major breakthrough in the germline transgenesis in Drosophila. However …

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[15 Jul 2009 | No Comment]
Targeted mutagenesis in Drosophila – SIRT

Guanjun Gao, Natalia Wesolowska, and Yikang S. Rong from the laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, have come out with a novel technique to knock out gene of interest in Drosophila. Its called SIRT , which combines various existing methods like homologous Recombination, Site-Specific Integration, and Bacterial Recombineering for targeted mutagenesis.
In SIRT, homologous recombination is used to place a landing site for the phage phiC31 integrase in the vicinity of the target locus. All subsequent genetic modifications to the same gene …

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[8 Jul 2009 | No Comment]
Post doc position to work on Ciona notochord tube formation

The Sars International Centre is a partner of the European Molecular Biology Laboratory (EMBL), and a department of Unifob, affiliated with the University of Bergen. The Centre is focused on basic research in marine molecular biology, developmental biology and evolution, through genetic and comparative studies of invertebrates and vertebrates.
The research group headed by Dr. Di Jiang is offering two postdoctoral positions. The group focuses its research on morphogenesis during animal development, more specifically on the tube formation process in ascidian Ciona intestinalis notochord.

Evo devo »

[8 Jul 2009 | No Comment]
Ginkgo biloba – A living fossil

Looking for a plant which can survive in any climate and soil ? Then species belonging to Ginkgo should be the answer ! Ginkgo species are known to be present on this planet since 270 millions years. Yes , that means they are around even before Dinosaurs (which flourished in Jurassic period 213 million years ago). The genus diversified and spread throughout the middle Jurassic and Cretaceous periods, but became much rarer thereafter. As we reached the end of the Pliocene, (The period in the geologic timescale that extends from …