Hoxful Monsters

Homeotic genes/ Hox genes encode transcription factors, which play an important role in giving a unique identity to each segment and thereby setting up morphogenesis along the anterior posterior axis.They are recognizable by the presence of a 60 amino acid long DNA binding region called the homeodomain,but all homeo domain containing proteins are not hox genes.Hox genes exhibit some important properties like
1) Found in clusters: Hox genes are physically linked on the chromosome.Eight genes are organized in one cluster in flies(Drosophila) and four clusters harboring 39 hox genes …

Organisms more complex than Sponges forms two or three tissue layers ,also called as germ layers.A germ layer is collection of cells formed during embryo genesis. Radially symmetrical cnidarians have two germ layers in endoderm and ectoderm making them diploblastic.Organisms with Bilateral symmetry produce one more additional layer between ectoderm and endoderm called mesoderm.These are called triploblastic organisms.These germ layers only give rise to tissue and organs in animals.
The endoderm forms: the stomach, the colon, the liver, the pancreas, the urinary bladder, the lining of the urethra, the epithelial parts …

Howard Hughes Medical Institute’s 2005 Holiday Lectures on Science series. Dr. Sean B. Carroll traces the development of evolutionary biology from Darwin’s voyage on the HMS Beagle through the advent of modern genetics.

Howard Hughes Medical Institute researcher Sean Carroll discusses the forces that shaped his decision to pursue a career in molecular biology
With these you might realize how much i like the work being done by Sean carroll
Here is another video of Sean carroll where he discusses the science of evolution and the field of evo-devo.

Richard Benedict Goldschmidt was a German born geneticist who is very well known for his work of “The material basis of Evolution” and controversial hypothesis of “Hopeful monsters”.Goldschmidt studied medicine at heidelberg with otto butschli . He worked in Germany for some years and during the second world war he moved to University of California,Berkeley.He has written many books but his magnum opus came in 1940 “The molecular basis of Evolution ” was his biggest contribution to the field of Evo Devo.
Goldschmidt was an unorthodox geneticist who didnot …