At first glance, the left and right sides of our bodies are identical to one-another. However, internally, as we dig deeper, some of our visceral organs are displaced to one side. Our hearts are larger on the left than the right, brains also show significant differences and when one take a look at long coil of guts with appendix near one end, it generally folds one side or to the another – but most interesting aspect for biologists in the field is that how things so consistently folds over in …

Injection of double stranded RNA in beetle larvae can be used to induce targeted systemic RNAi. This video provides an overview of the beetle injection technique used by Dr. Yoshinori Tomoyasu and his beetle lab at Miami University in Oxford, Ohio.
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The reverse genetic technique, RNA interference ( RNAi) has revolutionized the field of researach in life sciences as a potential means to silence genes in majority of organisms.RNAi is a phenomenon , in which introduction of double stranded RNA into the cell causes destruction of corresponding mRNA, thereby silencing that particular gene.
The mechanism of RNAi pathway is well know based on work in c.elegans and other model systems in the field.The RNAi pathway is initiated by the RNaseIII nuclease Dicer, which chops dsRNA into 21–23 bp fragments which are later …

A new review article on insect RNAi has been published in journal of invertebrate pathology ( articles in press section)authored by John Burand and Wayne hunter, the review article deals with various aspects of RNAi mechanisms in Insect cell lines and the ways to use RNAi technique to control pests.The review also gives a decent account on problems encountered while performing RNAi in insects and whats in store in the field of RNAi in Insects. (349)

Introduction and History of RNAi
The phenomenon of RNA interference (RNAi) was discovered for the first time in nematode Caenorhabditis elegans. Subsequently RNai mechanism was also found to be conserved in different organisms ranging from plants to Drosophila and Humans. RNAi is a well conserved sequence specific gene silencing mechanism induced by double stranded RNA (ds RNA), resulting in degradation of the targeted mRNA. It plays a pivotal role in regulation of gene expression, participates in defense against viral infections, and keeps jumping genes under control. While RNAi is an endogenous …

On Wednesday, May 18, 2011, in a live, online educational seminar, “Identifying Novel Cancer Therapeutic Targets: Real-time, Label-free Cell Monitoring in RNAi Profiling.”
Date: Wednesday, May 18, 2011
Time: 12 noon Eastern, 9 a.m. Pacific, 4 p.m. GMT, 5 p.m. UK
Duration: 1 hour
Register now and submit your questions LIVE to the experts during the webinar! (168)

Andrew Sinclair’s group in Murdoch children research institute in Australia deciphered the mechanism involved in avian sex determination, which has been a long-standing mystery in the field of developmental biology. Prof Sinclair’s group focuses on sex determination, and aims to understand how genes control gonad development. Development of the gonads (testes or ovaries) requires the coordinated functioning of many genes and proteins.
Sex determination in Birds like mammals is chromosomally depended but sex chromosomes as well as mechanism is largely different. All males in Birds possess have two Z chromosomes while …