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Articles in the HOX Category

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[8 Mar 2013 | No Comment]
Antagonism Versus Cooperativity with TALE Cofactors at the Base of the Functional Diversification of Hox Protein Function

Here is another article on Hox -TALE interaction published in PLOS genetics last month. (2012)

Featured, HOX »

[22 Jan 2013 | No Comment]
Hox Gene AbdB controls left right asymmetry in Drosophila – Part II

Extending further from their work published in Nature journal (321)

Featured, HOX »

[22 Jan 2013 | No Comment]
Hox Gene AbdB controls left right asymmetry in Drosophila – Part I

At first glance, the left and right sides of our bodies are identical to one-another. However, internally, as we dig deeper, some of our visceral organs are displaced to one side. Our hearts are larger on the left than the right, brains also show significant differences and when one take a look at long coil of guts with appendix near one end, it generally folds one side or to the another – but most interesting aspect for biologists in the field is that how things so consistently folds over in …

HOX »

[16 Jan 2013 | No Comment]
Identification of cardiac enhancers in Drosophila – Direct targets of tinman gene

In Drosophila melanogaster, heart precursor cells originate from the dorsal-most region of the mesoderm in response to Decapentaplegic(dpp) and wingless (wg) signalling. These cardiac precursor cells later form heart-like organ called the dorsal vessel. The Drosophila heart is a simple organ composed of two major cell types: cardioblasts, which form the simple contractile tube of the heart, and pericardial cells, which flank the cardioblasts. (1853)

Evo devo, HOX »

[8 Jan 2013 | No Comment]
Functional conservation of mosquito’s boundary elements in Drosophila – Insights into regulation of Hox genes by evolutionary conserved mechanisms

Hox genes are evolutionarily conserved and play significant roles in providing segment specific cues along the anterior-posterior (AP) axis of all bilaterian embryos. The study of Hox genes has been extensively carried out in Insects where they assign identities to appendages, such as mouthparts, antenna, wing, halters and legs (ectoderm derivaties) along with patterning the mesoderm and gut endoderm along the A–P axis. (1932)

Evo devo, HOX »

[17 Dec 2012 | No Comment]
Hox genes in Insects – Isolation of Hox genes from 6 different Insect orders

Hox proteins provide positional cues along the anterior posterior axis in majority of animals on this planet. This positional information is crucial in segment specific morphogenesis. Hox proteins is a part of antennapedia class of proteins, which consists of about 100 genes in bilaterians , divided into 30 gene families belonging to four major groups: HOX / PARAHOX genes (45 genes, four gene families), HOX-related genes (nine genes, five gene families), NK genes (16 genes, seven gene families), and NK-related genes (28 genes, 18 pseudogenes, 14 gene families). (953)

HOX »

[7 Jun 2011 | No Comment]
New Book on Hox genes – Edited by Jean Deutsch

A new book dealing with Hox genes titled Hox genes studies from the 20th to the 21st century under the series of Advances in Experimental medicine and biology , Vol 689 . This book published by Springer Books is edited by jean deutsch and 12 different chapters written by various experts in the field of Hox biology. (294)