New Book on Hox Genes: By Olivier Pourquie
The latest issue of Current Topics in Developmental Biology features all the chapters of the new book on Hox genes ,which is edited by Olivier Pourquie. The hardbound copy of the book can be bought online from springer and Amazon.However one needs a subscription to the journal to see the full text of the chapters from the book.
This book has several interesting chapters covering all important aspects of these master regulator genes and also has Preface by Olivier Pourquié.I have started reading the first three chapters (as they are more related to the work i am presently doing) and can surely say that they are very well written and can easily be understood. My particular favorite is the one by Richard Mann on the one of the Hox paradox related to the specificity aspect invivo.
Chapters information:
Preface Olivier Pourquié
Chapter 1 The Bithorax Complex of Drosophila: An Exceptional Hox Cluster
Robert K. Maeda, François Karch
Chapter 2 Evolution of the Hox Gene Complex from an Evolutionary Ground State
Walter J. Gehring, Urs Kloter, Hiroshi Suga
Chapter 3 Hox Specificity: Unique Roles for Cofactors and Collaborators
Richard S. Mann, Katherine M. Lelli, Rohit Joshi
Chapter 4 Hox Genes and Segmentation of the Vertebrate Hindbrain
Stefan Tümpel, Leanne M. Wiedemann, Robb Krumlauf
Chapter 5 Hox Genes in Neural Patterning and Circuit Formation in the Mouse Hindbrain Yuichi Narita, Filippo M. Rijli
Chapter 6 Hox Networks and the Origins of Motor Neuron Diversity
Jeremy S. Dasen, Thomas M. Jessell
Chapter 7 Establishment of Hox Vertebral Identities in the Embryonic Spine Precursors Tadahiro Iimura, Nicolas Denans, Olivier Pourquié
Chapter 8 Hox, Cdx, and Anteroposterior Patterning in the Mouse Embryo
Teddy Young, Jacqueline Deschamps
Chapter 9 Hox Genes and Vertebrate Axial Pattern
Deneen M. Wellik
Book Description:
A subgroup of homeobox genes, which play an important role in the developmental processes of a variety of multicellular organisms, Hox genes have been shown to play a critical role in vertebrate pattern formation. Hox genes can be thought of as general purpose control genes-that is, they are similar in many organisms and direct the same processes in a variety of organisms, from mouse, to fly, to human.
* Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area.
* Inclusion of chapters that discuss the evolutionary development of a wide variety of organisms.
* Gives researchers and clinicians insight into how defective Hox genes trigger developmental abnormalities in embryos.
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